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Institute for Translational Medicine and Therapeutics

The Institute for Translational Medicine and Therapeutics (ITMAT) supports research at the interface of basic and clinical research focusing on developing new and safer medicines. ITMAT includes faculty, basic research space, and the Center for Human Phenomic Science (CHPS), which includes both Penn and the Children’s Hospital of Philadelphia (CHOP). ITMAT also offers research cores, research programs, research centers, and educational programs in clinical and translational science for researchers and research support staff.

Our Focus

Cores

Our Work

Recent Publications

Bdellovibrio predation cycle characterized at nanometre-scale resolution with cryo-electron tomography.

Nature microbiology. 2023 Jun 22; Authors: Kaplan M, Chang YW, Oikonomou CM, Nicolas WJ, Jewett AI, Kreida S, Dutka P, Rettberg LA, Maggi S, Jensen GJ

Structural basis of purine nucleotide inhibition of human uncoupling protein 1.

Science advances. 2023 Jun 2;9(22):eadh4251 Epub 2023 May 31; Authors: Jones SA, Gogoi P, Ruprecht JJ, King MS, Lee Y, Zögg T, Pardon E, Chand D, Steimle S, Copeman DM, Cotrim CA, Steyaert J, Crichton PG, Moiseenkova-Bell V, Kunji ERS

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